Sen'Derrick Marks is doubtful for Sunday's season opener against the New England Patriots after missing his third straight practice this week with a sprained MCL in his right knee.
Marks' likely absence could give rookie third-round pick Mike Martin the start at defensive tackle on Sunday, alongside Jurrell Casey, who is listed as questionable himself with an elbow injury. Casey did practice fully all week.
Second-year pro Karl Klug, who led the Titans with seven sacks as a rookie last year, could also see an increased role if Marks cannot go. Undrafted rookie DaJohn Harris could also see an increased role on Sunday.
"Obviously, having Klug, and especially in this game, when they’re going to be throwing the ball quite a bit, you have him," Titans coach Mike Munchak said. "We’re happy with Mike Martin, how well he played. He came on strong here in the last preseason game. We’re confident with him and also with the young guy we kept. We think Harris can go in there and give us some reps too if that’s the case. I think we feel good with that."
Also questionable are linebacker Zac Diles (hamstring), who practiced all week, defensive end Scott Solomon, who practiced Friday for the first time since having his right knee scoped last week.
Backup offensive tackle Mike Otto is out for the game following having his knee scoped and surgery on his hand during preseason.